David Lee’s Under-23s will take on their Barnsley counterparts on Monday evening in the Professional Development League at the County Ground, kick off 7pm.
Wanderers will be looking to bounce back from their 2-0 defeat away at Leeds United last Monday as they currently sit fifth in the league.
The Whites currently sit on 32 points, with a victory potentially seeing the Whites jump up to fourth spot.
The young Tykes side meanwhile are coming off the back of a 1-1 draw against Nottingham Forest.
With 28 points on the board from a possible 63, Martin Devaney's side will also be hungry to build on their impressive unbeaten run of five games in the Professional Development League.