In-form Wanderers make a rapid return to the University of Bolton Stadium and go in search of a third successive home win.
The Whites have also chalked up a 1-0 success at Shrewsbury Town during their current impressive run which has lifted them to 15th place in the table.
Cambridge have also been going well with their only defeat in eight games a penalty shoot-out loss at Rotherham in the Papa John’s Trophy.
The U’s – promoted alongside Wanderers last season – also have a fourth-round FA Cup tie against Luton Town to look forward to on Saturday after knocking out Newcastle in round three.
But Ian Evatt’s will go above them in the table and could go as high as 11th if they can back follow up Saturday’s 6-0 win over Sunderland with another three points.
Pre-match quotes: From the bosses
Ian Evatt: “I thought Saturday was excellent but Tuesday will be equally difficult in different circumstances; an equally challenging game.
“As good as it felt and was on Saturday, it’s back to business now with a big game.
“We’ve got to manage that the same way and have the same intensity and work ethic we had on Saturday and give it the same importance.
“And if we do that we’ve got a chance of winning the game.”
Mark Bonner: “I think if we look at Januarys for both teams over the last two years, we’ve both been exceptional, in terms of results.
“Both seasons has seen a transformation of their squad. Some real senior players have left in recent weeks but they’ve re-invested well on some excellent players.
“I think the strength of their team and squad at the minute is very good.
“They come into the game off the back of an incredible result.
“I’m sure they will be full of confidence and looking to back that up with another strong performance against us.”
Wanderers are unable to include final January arrival Kyle Dempsey after the midfielder signed after the cut-off point to play tonight.
But boss Evatt has no fresh injury concerns in a squad strengthened by seven new arrivals since the turn of the year.
Cambridge are expected to have Lorent Tolaj in their squad following the striker’s loan signing from Brighton but top scorer Joe Ironside is likely to miss out through injury.
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Last time out
Wanderers 6-0 Sunderland 0 | Saturday 29 January, 2022
Wanderers enjoyed a history-making day as they beat promotion-chasing Sunderland 6-0.
The victory was the Whites’ biggest ever at the University of Bolton Stadium.
Dion Charles scored his first home goals in a classy double, with Dapo Afolayan, Kieran Lee, Declan John and an own-goal wrapping up a third successive league win.
Line-up: Trafford; Jones, Santos, Johnston; Fossey, Williams, Morley, John; Lee (Bakayoko 72); Charles (Sadlier 72), Afolayan (Bodvarsson 72). Substitutes: Dixon, Aimson, Thomason, Baptiste.
Referee: Andy Haines
Assistant referees: Johnathon Bickerdike and Steven Rushton
Fourth Official: Robert Lewis