Wanderers head south on the weekend following their emphatic victory 3-0 victory over AFC Wimbledon last time out.
That win ended a run of four consecutive 1-1 draws with the Whites now heading to Orient on a six game unbeaten run.
Leyton Orient got back to winning ways last weekend at Vale Park following on from two previous league defeats against Northampton Town and Mansfield Town.
The O's in their last five outings have two wins, two defeats and a draw. Both victories came on the road, the forementioned victory against Port Vale and a 1-0 triumph over Plymouth Argyle.
Press Conferences
Steven Schumacher: "I think it will be an exciting game. I'm really looking forward to it because it'll be a different style of game than what we've faced in the last few.
"They are probably unlikely to play a back five, which is what we've faced recently, and they're a team who definitely like to attack.
Leyton Orient Boss Richie Wellens: "They have got good footballers. They have two good wingers, whichever two play. They have obviously recruited really well.
"(Mason) Burstow was someone we liked, (Marcus) Forss is an unbelievable signing for the level and they have good midfield players who can handle the ball.
Team News
Midfielder Josh Sheehan and Captain Eoin Toal return from international duty for Wales and Northern Ireland respectively.
Mason Burstow has got the all clear following a hamstring scare on Saturday. He was substituted following Amario Cozier-Duberry's second hlaf goal but went for a scan on Monday and there was no damage to worry about.
Kick-off
Saturday 3pm
Referee
David Rock will take charge of this fixture.
Tickets/Wanderers TV
Away tickets for Leyton Orient are SOLD OUT.
For those not going to the game, audio passes will be available, as always, for UK-based supporters to listen to full commentary with Derek Clark and John McGinlay via Wanderers TV. Those based internationally can stream the game through a live video match pass on Wanderers TV.
Click HERE to purchase a pass.