Steven Schumacher makes three changes to the side that came away with The Valley as victors on Tuesday night.
There's change across the midfield, as Thierry Gale, Ruben Rodrigues and Gaizka Larrazabal come in, replacing Max Lott, Samuel Illing-Junior and Atsuki Ito, who all begin tonight's game on the bench.
While Gavin Bazunu remains out through injury, the Wanderers will be boosted by Josh Sheehan coming through a late fitness test to start the fixture against The Rams.
Meanwhile, the hosts have opted to make six changes to their side, following the four-nil defeat to Norwich on Tuesday night. David Odoh returns from injury to start tonight's game, while Shane Duffy comes in to make his debut for John Eustace's side.
Wanderers: Bonham, Forino, Simons, Sheehan, Dalby, Gale, Famewo, Rodrigues, Larrazabal, Conway, Stephenson. Substitutes: Harrington, Brunt, Davies, Dong, Bair, Watson, Illing-Junior, Ito, Lott.
Derby County: Zetterstrom (GK), Odoh, Clark, Morris, Brewster, Robinson, Fuselini, Nyambe, Duffy, Travis, Sanderson. Substitutes: Vickers, Bilbija, Salveson, Mowatt, Johnston, Fraulo, Blackett-Taylor, Canoville.