Wanderers make ten changes following their FA Cup exit on Saturday.
Captain Eoin Toal is the only player who remains from that defeat on the weekend. Teddy Sharman-Lowe, Cyrus Christie, George Johnston and Max Conway all come in at the back.
Xavier Simons returns to the side after his suspension was served against Swindon. He is joined by Ethan Erhahon.
Marcus Forss and Jordi Osei-Tutu start on the wings with Kyle Dempsey just behind Mason Burstow upfront.
Wanderers | Sharman-Lowe, Christie, Toal, Johnston, Conway, Simons, Erhahon, Forss, Dempsey, Osei-Tutu, Burstow
Substitutes | Miller, Forino, Sheehan, Randall, Cozier-Duberry, Gale, Dalby
Mansfield Town | Roberts, Hewitt, Oshilaja, Cargill, Blake-Tracy, McDonnell, Reed, Akins, Lewis, Evans, Oates
Substitutes | Mason, McLaughlin, Sweeney, McAdam, Moriah-Welsh, Dickov, Dwyer
Referee: Thomas Parsons