Wanderers hand a league debut to teenage defender Sam Inwood as manager Steven Schumacher makes six changes to an injury-hit side.
With 12 senior players unavailable, the Whites name four youth-team players on the bench along with B Team defender Sean Hogan.
Youth captain Harley Irwin is joined among the substitutes by Harrison Rice, Daeshon Lawrence and David Abimbola as Wanderers look to halt a run of four successive defeats in their final away game of the campaign.
Szabi Schon returns from a five-match injury absence and there are also returns to the starting line-up for goalkeeper Luke Southwood, Klaidi Lolos, John McAtee and former Peterborough man Joel Randall.
Vertu Trophy winners Peterborough also name a much-changed and youthful line-up after confirming their League One status over the Easter weekend.
Wanderers: Southwood, Jones, Murphy, Thomason, Lolos, Forino, Schön, Matete, Randall, McAtee, Inwood. Substitutes: Baxter, Collins, Abimbola, Irwin, Lawrence, Rice, Hogan.
Peterborough United: Blackmore, Mills, Nevett, Hughes, Johnston, De Havilland, O’Brien-Brady, Mothersille, Odoh, Conn-Clarke, Lindgren. Substitutes: Steer, Dornelly, Kyprianou, Mendonca, Jones, Poku, Shofowoke.
Referee: Ruebyn Ricardo