Top scorer Aaron Collins returns to lead the Whites’ attack as Wanderers look to close the gap on the top six.
Collins – back from injury as a substitute for the mid-week Vertu Trophy exit – starts as one of four changes to the side that lined-up against Crawley Town for last Saturday’s thrilling 4-3 league win.
Gethin Jones, George Johnston and Jay Matete are also named by boss Steven Schumacher and with George Thomason serving the second game of a two-match league ban, Eoin Toal again captains the side on his 26th birthday.
Chris Forino earns a place on the bench with the defender in the squad for the first since since September after recovering from a hamstring injury.
Shrewsbury, unbeaten in four home games in their battle to beat the drop, give a full debut to on-loan Bradford City striker Vadaine Oliver.
Wanderers: Southwood, Jones, Murphy, Johnston, Morley, Toal, Collins, Matete, Randall, McAtee. Substitutes: Baxter, Dacres-Cogley, Forino, Sheehan, Schön, Osei-Tutu, Adeboyejo.
Shrewsbury Town: Blackman, Hoole, Benning, M Feeney, J Feeney, Oliver, Ojo, Perry, Gape, Gilliead, Marquis. Substitutes: Savin, Biggins, Dinanga, Nsiala, Nurse, Stewart, Shipley.
Referee: James Durkin