Steven Schumacher has made three changes to his side that beat Wolves on Tuesday night, ahead of the fixture today against Southampton.
Defender Luca Stephenson completes his return to fitness to play this afternoon, his first competitive fixture since the first game of the season against Preston.
Striker Sam Dalby also returns to the Starting XI ahead of Thelonious Bair, who was rewarded with a first Bolton start on Tuesday night.
The final change from Tuesday night is midfielder Xavier Simons, coming in for Ethan Erhahon, who starts the match on the bench.
The Saints have made six changes to their starting lineup that played at Carrow Road on Wednesday. Midfielder Cameron Bragg returns to the lineup following his suspension, while Leo Scienza and Tom Fellows both also return to The Saints’ starting XI, after starting on the bench against Norwich.
Midfielder Flynn Downes misses out today's match through injury, while Kuryu Matsuki - who scored the only goal of their midweek fixture - also drops to the bench today.
Wanderers: Bazunu, Stephenson, Toal, Brunt, Famewo, Sheehan, Simons, Larrazabal, Ito, Gale, Dalby. Substitutes: Bonham, Davies, Conway, Erhahon, Illing-Junior, Bair, Rodrigues, Hardie.
Southampton: Peretz, Azaz, Bragg, Bree, Fellows, Larin, Schlotterbeck, Scienza, Stephens, Ward-Prouse, Welington. Substitutes: Abbott, Dobbin, Edozie, Jander, Long, Manning, Matsuki, Mubama, Wood.