Wanderers make five changes to their starting line-up for the first of two away games in five days.
Striker Thelonious Bair is rewarded with his first goal for the Whites in last Saturday’s defeat to Stoke City with a full debut at Molineux.
Boss Steven Schumacher also names defenders Lewis Brunt and Akin Famewo, winger Samuel Iling-Junior and attacking midfielder Atsuki Ito – who also gets a first start after scoring the winner in Wanderers’ last away trip – in his side to tackle Wolves.
Former Aston Villa youngster Max Lott is included in a match-day squad for the first time as the teenage winger earns a place on the bench on his return to the Midlands.
Wolves – fifth in the Championship table and defending an unbeaten home record – make four changes to the side that lost 1-0 at Middlesbrough on Saturday.
Wales international midfielder Jordan James makes his first EFL start for the Midlanders after signing in the summer from Rennes.
Wanderers: Bazunu, Brunt, Sheehan, Bair, Gale, Famewo, Iling-Junior, Ito, Toal, Erhahon, Larrazabal. Substitutes: Bonham, Simons, Davies, Dalby, Rodrigues, Conway, Nelson, Lott, Hardie.
Wolves: Sá, Trippier, Bueno, André, James, Armstrong, Bellegarde, López, Djiga, Mané, Krejcí. Substitutes: Virgínia, Munetsi, Neave, Saïd, Doyle, Chirewa, Toti, Konan, Tchatchoua.
Referee: Tim Robinson